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ABSTRACT
| Ethnobotanical Survey and Antibacterial Activity of Boswellia dalzielii (Frankeninsence) against Vibrio cholerae in Sokoto State, Nigeria |
| Salma M. Galalain1*, Sanusi Muhammad1, Habsatu Shehu1, Shuaibu A. Hudu2,3 |
| Background: Ethnobotany is the study of the indigenous or traditional knowledge of plants. Cholera is a diarrheal disease caused by Vibrio cholerae, a Gram-negative rod-shaped bacterium. Materials and Methods: The initial ethnobotanical study was conducted using questionnaires given to respondents across Sokoto state, plants with the highest citation were collected after the survey. Standard methods were used for Qualitative and Quantitative Phytochemical Screening. Antibacterial analysis was performed by the agar well diffusion method, and its MIC and MBC were also assessed. Results: The biodata shows male respondents everywhere, herb sellers were the main distributor of the medications, Elderly people between the age group of 51-60 years have more knowledge of the plants, most of the respondent has no formal education and water is the main medium how the plants are prepared. Phytochemical analysis showed the presence of various secondary metabolites, which are abundant and its biological properties act as natural antibiotics and protects human body from the microbes infestation. The plant extract from the aqueous extract of Boswellia dalzielii inhibited for both the ATCC standard strains and clinical isolates of Vibrio cholerae collected, with the highest inhibition of 14.83 mm shown at 300mg/ml by the ATCC standard strain and a clinical isolate with an inhibition of 13.00mm at the same concentration. Clinical isolate has no inhibition 6.80 mm with 100mg. ATCC standard strain is more sensitive than clinical isolate. Conclusion: The study suggests that Boswellia dalzielii could be able to treat Gastrointestinal tract infections; further work needs to be focused on the factors involved in resistance of the clinical isolates. Ethnobotanical surveys need to be carried out to identify other plants used by the local communities for treatment of Cholera disease. Therefore, it is necessary to describe compounds after isolation & purification of bioactive components because chemical constituents may give high level of antibacterial activities which serve the plants as a source of new valuable drugs. |
| 10.51658/ABMS.202452.13 |
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